Peptides for Skin, Longevity, and Metabolism
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CHRISTA ELZA: [00:00:00] this peptide in your body helps produce collagen. Which promotes elasticity and skin cell turnover. It's also anti-inflammatory, so you can use it for more than just skin health, but the amazing effect is that it helps promote more of a glowy like collagen producing.
Skin and appearance.
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SHEREE BEAUMONT: Welcome back to another episode of the Wild and Wild Collective. Today we are doing part two, all Things Peptides. We're actually gonna dive in a little bit deeper and discuss some of the really specific ones that you can take, whether you're looking at gut health, muscle mass, whether you're looking at optimizing sleep and longevity.[00:01:00]
Or you know, we have done a beautiful deep dive, a little bit more into the GLP ones, which you'll find in our part one, just more talking about the fat loss. But we're gonna be looking at things a little bit more specifically from a metabolic health perspective too. So, Krista, I'd love for us to start with.
I didn't mention in the intro, but I'd love for us to start with the one around skin health because I think, you know, there's this huge thing around anti-aging. I'm a little bit biased here and I wanna learn about it for myself. You know, is the peptides that are out now like an alternative to Botox?
Are they something that works well along well with that? Are we gonna see reduction in fine lines and wrinkles? Is it something that helps with acne? Like when we talk about these peptides, that can seem like a really foreign concept and. How it impacts our skin and aging. How does that work?
CHRISTA ELZA: Yeah, so I think you're talking about the GHK copper.
So this peptide has become really popular. You'll hear it in as a combination with the glow peptide or the CLO [00:02:00] peptide. These are examples of peptide stacking, which we'll talk a little bit about. But GHK copper is in both of those. You can also do GHK copper by itself. So we have this peptide in our body, much like most of the peptides that you're hearing about.
We, we do have this GHK helps to, and it's attached to a copper. So that's why people call it a copper peptide. But this actually, this peptide in your body helps produce collagen. Which promotes elasticity and skin cell turnover. It's also anti-inflammatory, so you can use it for more than just skin health, but the amazing effect is that it helps promote more of a glowy like collagen producing.
Skin and appearance. So it's not gonna be a replacement for Botox or fillers, but it will help the skin texture, it will help the support of the skin, which declines with age like collagen will decline with age. So you can do the copper peptides in combination. I actually have currently have. One [00:03:00] for like a topical that I've combined with estrogen, which is cool.
So, you know, as you hit your forties, like estrogen will start to decline. And so, we have receptors all over our body and so you can combine it with cool things like, like estrogen. Copper peptides are also combined with BPC and TB 500, which help healing and skin, you know, cellular turnover.
So you can combine it with that. That's the glow peptide. And then some people will also combine it with those three. But then an additional peptide called KPV, which is also really healing orally. KPV can be helpful for gut healing. But when you combine it with in an injectable form with that GHK copper, then that also can help inflammation in the skin collagen production.
So it's kind of a whammy having all of these kind of stacked together, which is really cool.
SHEREE BEAUMONT: I love that. So if you were just, you know, new to this world, is there like with this, all of the [00:04:00] peptides and you're like, okay, like I'm seeing all the hype and anti-aging is really important to me. Like at what age do you start? Like I'm going, do I need to be on these from now? Like I'm in my early thirties and I wanna be promoting like optimal health and longevity.
Is there like too soon to start? Is there like an optimal age start? I can always remember my mom telling me, like when I hit 25, she's like, you need to start looking after your skin now 'cause you're collagen is starting to go down. So like what? What's kind of the advice around when people are starting to look into this or maybe wondering if they should investigate?
CHRISTA ELZA: Yeah, I think that prevention is key. So you know, in my book, why wait till something's a problem to start when you can just stave off, you know, the happening of wrinkles and all that. Anyway, so in terms of JHK Copper, I don't think that there's any. Age that, I mean, it's as safe across the board as an adult age.
You could start it just as preventative. So I definitely think, and you'll see some of this stuff combined in just skincare, you'll see peptides all over the place. Even [00:05:00] in over, you know. On the shelf right in in the stores, you're not gonna get the potency that you will from a compound pharmacy or you know, someone that's going through third party testing, et cetera.
So I'd be really mindful about where you're getting these peptides, but I don't think that there is an age that's too young to start just as a, and preventative measures for that.
SHEREE BEAUMONT: beautiful. So I can get started tomorrow. on the topic of like longevity, what are some of the peptides that you're seeing kind of commonly being stacked and maybe 'cause we are ref referring to peptides, stacking quite a bit in this episode.
Do you wanna explain a little bit first about what peptide stacking is and then go into like maybe a longevity stack that most people might be interested in?
CHRISTA ELZA: Yeah, so peptide stacking is just that. It's taking multiple peptides, not necessarily in the same vial because not all peptides can be combined chemically in the same vial, but it's taking it concurrently.
So, for instance, in the growth hormone secretagogues, those are peptides that are gonna help the hypothalamus to push out. So [00:06:00] in your brain, you're gonna push out growth hormone. That declines after your twenties. These peptides will stimulate the pituitary to then push this out again when you have when you have deep sleep.
And so there's a variety of them. One of them, Lin, which has been around for a long time, especially in the bodybuilding world because it helps to promote that growth hormone, so you'll have better muscle mass. Some of these also though, the side effect of them can be increased appetite. And so this is just an example.
You could take some morelin that might help you sleep better, might help promote growth in the muscle maintenance of the muscle, but then you're finding that you're really munchy, so then you might wanna stack that. So concurrently you're taking a GLP one that's gonna curb appetite. So that's kind of an example of stacking.
There's also stacking in the same vial. So C, J, C and Ipamorelin. Those are both growth hormone secret goss as well. I prefer epi morelin over Lin for that reason that it [00:07:00] doesn't create as much of a side effect of hunger. It's not to say that it's not there, but it's not as extreme sometimes in the Erlin.
But that's an example of stacking in the same vial. Another one, as long as we're talking about growth hormone, Testim, Molin is another one that can also help with belly fat. So I've put, you know, women. Men and women both love this, but women who are kind of frustrated with that midsection growth, of course men have the dad, bo, and the, you know, so we'll combine Tess Morelin, which helps growth hormone.
But also helps lipolysis of the fat and particularly around the midsection, which can be really helpful. So I'll stack Teim, Molin, and I molin and those can actually be in the same vial, which is just helpful 'cause then you're not having to do two sticks. So that's hap that's kind of stacking them.
And that's also a little bit of an explanation of some of the varieties that we have. Just to help promote better fat metabolism and growth in terms of like muscle mass. There's another peptide that I'll see sometimes out and about [00:08:00] and people ask for it sometimes is. The a OD 9, 4 0 6 I believe is that that one can also help with fat metabolism.
So it helps to with like fat lipolysis. Some of these don't do well on their own. They do better synergistically. So the a OD peptide, I would recommend taking that while concurrently, while you're taking a GLP one, because it can augment the GLP one. But on its own, I don't know, I don't think people see the effects that they want just based on hearing what it does.
It actually works better synergistically taking the same time as a GLP one.
SHEREE BEAUMONT: Okay. And you talked a little bit about the midsection, which I know men don't go through menopause. But it's a really common issue, right? That midsection weight gain, particularly for women in perimenopause and menopause.
And they kind of feel like they're hitting up against a brick wall and they're trying everything. And like we've mentioned before, like their hormones are absolute chaos. Like, yes, you can eat the protein, yes, you can wait train. Yes you can do all the [00:09:00] lifestyle changes, but sometimes it can be helpful to have a little bit of assistance.
One of the things that I know supports like our mitochondrial health and our longevity, but can also be supportive and potentially, I'd love for you to talk to this in combination with the GLP one is the Mott C. So can you explain a little bit about that peptide and how it can kind of work, especially in this age of well that age or stage of life?
CHRISTA ELZA: Mm-hmm. So Motzi is popular among men and women. Motzi works by helping the body become more insulin sensitive. So I'll use this a lot with people who are having a hard time with insulin sensitivity. I will say when people are using like growth hormone promoting growth hormone directly or even the secreted dogs, sometimes you can have some insulin resistance.
Not so much with the secreted dogs, which is why they're safer than doing growth hormone. Directly. So like the Telin and the IOR and smolin, those are safer. But some people will stack those with motzi because an [00:10:00] increase in growth hormone sometimes can create some insulin inti resistance. And so motzi works by helping to the metabolism in that way helps your body use glucose more efficiently.
It helps the mitochondria have be more fueled. So it helps the body to actually take the food that you're eating, the energy that you're consuming and convert it into usable energy in the body, which then in turn creates better meta mitochondrial health. And we know that as we age the mitochondria, we don't have as much.
We can have you know, less healthy mitochondria. And if you remember in science, mitochondria is an organelle in the cell, and that's what produces the A TP, right? The cash flow of energy. And so we want to have good, healthy organelles. We wanna have good, healthy mitochondria in the cells, and so motzi can work in that way, so it can help you better with energy and energy utilization overall, which we know declines with age.
So they can be really [00:11:00] helpful in that period of menopause or andropause for men as their testosterone levels are declining.
SHEREE BEAUMONT: Yeah, it's really beautiful to hear that it's working on. A cellular level. You know, I think a lot of the times when we're taking injections or we're putting things into our body, it's often trying to mitigate one's symptom or it's a bandaid, which is where I'm healing.
Like hearing the real difference with peptides come through. And I mean in our last episode on this, you did talk a lot more in depth around the gut healing and you know, even some of the muscle mass and that sort of thing. So just high level summary of. The peptides you can use from this deeper healing perspective that people might wanna be starting off with.
And then I'm really curious, like is it just. You have a look at people's markers. You do their testing, like they look at their bloods, and then can you kind of just create your own little peptide stack? Like I was like, look, I wanna optimize my mitochondrial health and make sure I'm doing everything I can to optimize my cellular function.
Looking at like the mot C, maybe I don't, I'm like, I'm not [00:12:00] really interested in the GLP ones at this point. I don't feel like I need to lose any weight, but hey, I want to. Make sure my body is recovering really well, my gut's really healthy. Like can you just kind of come up with, is that what you do? Like you just come up with a little personalized stack?
Is that how it works?
CHRISTA ELZA: Yeah, I joke that like when you start into the world of peptides, it's almost like walking like a kid in a candy store. You're just like, oh, I wanna try that one, and that one and that one. 'cause the more you learn about it, you're like, well, yeah, I wanna optimize this and that. And there's so many just variations in the, I think, you know, with science and research, it's only gonna grow.
Yes. So it's kind of based on symptoms. What are people's interests in either optimizing healing. Staying ahead of things, you know, prevention, all of that. So it really does depend. I would use something like motzi, like I said, if you've got some insulin resistance alongside a GLP one can be really empowering and powerful for the body.
Alon is epitol. There's different ways to pronounce that one. That particular [00:13:00] peptide is actually a bio regulator, so it's a very short chain of amino acids. And this one actually helps to heal. If, you know, on our DNA strands, we have what are called telomeres, which are kind of the shoelaces, the end of the shoe lace, and the shorter the telomeres the more aged you are cellularly.
So when we can increase that length. We know that the cell age, the DNA, is actually healthier, which is important when we're talking about cancers. We're talking about, you know, DNA malformations and things like that. Cell turnover. So you know, brain health, skin health, energy, everything. Epitol or peton, however you wanna say that one does help the link.
The health of the DNA strands helps the body function in interesting ways, so it can kind of be in that anti-aging bucket in general. This one, you actually don't do month by month. You can just do two or three times per year. You don't need [00:14:00] to have it year round. But it can be helpful in DNA health.
It can also be helpful all the way down to like lipid. So, you know, people have been shown to have lower LDL and higher HDL, which the, is the good cholesterol with a couple of rounds of this bio regulator. So it's really cool like looking at blood work and then kind of saying, matching a peptide to either what they're interested in, what their pain point is or what their blood work is showing.
We can't see mitochondria mitochondrial health directly in blood work, but we certainly can make. We can deduce that like mitochondrial function is sluggish when we have, you know, high lipids, low energy high homocysteine, folic acid, et cetera, or I'm sorry, low folic acid. I will say that motzi works on those pathways, on the methylation pathways.
So if you are on motzi, it is really good to be on a B complex because it can utilize more of that folate, the B nine, the B12. So, you know, just working with somebody you kind of [00:15:00] understands, hey. This peptide is great, but also it can deplete certain other nutrients, et cetera in the body.
SHEREE BEAUMONT: That segues perfectly into my last questions to kind of wrap this one up.
So we can't really look at this and then think, okay, I'm gonna replace a whole bunch of supplements. 'Cause I think that, that can be the thing, right? You come into this world of health and you're like suddenly taking 20 different pills. You're popping, like you're injecting yourself with 12 different peptides.
I'm over exaggerating, obviously, but you know what I mean. Like, I'm also hearing, you know, it may be that the Mott Sea or the GLP ones could replace something like a Berberine supplement. So like, how does it work? When we're looking at the overlap, I'm hearing you need to be complex. If you're on something like the mot.
C and that will enhance it. But there are probably some peptides that will remove the need for supplements. How does that all work?
CHRISTA ELZA: Mm-hmm. Well, just like different medications, you know, let's say statins, PCSK nine inhibitors, both of those lower lipids, right? But they do it through different mechanisms.[00:16:00]
So different classes do things through different mechanisms. And so you mentioned Moee and berberine. They're both gonna be used for insulin sensitivity, but they go through different mechanisms, through different pathways. Sometimes we have to stack two things to really get the effect that we want, so it's not necessarily contraindicated to combine certain things, but also it can eliminate the need for.
One or the other? I would say the peptides work in a different way, that they work more with your body and help your body kind of get in line better because of the, what they are, because they're amino acids. Because they are, most of these are found naturally in our bodies, so we're kind of upregulating something that we already make in our body.
So our body recognizes that. Our body sees it as not foreign. It sees it as part of us. Part of your, chemistry anyway, which is really cool. So yeah, I think it definitely can eliminate some supplements and honestly, if you're working with someone who's doing peptides, you really should be looking at blood work and kind of having targeted [00:17:00] supplements anyway, rather than just taking a whole bunch because you saw it on TikTok or whatever.
You wanna kinda have targeted supplements for what you need and we don't always need the same supplements all the time. Like that could change. And so periodically checking every six months or so, blood work. Checking in with symptoms, et cetera, is really. Something that you should be doing anyway.
SHEREE BEAUMONT: Beautiful. I love this and I feel like I've learned a lot and I'm excited to dive more into the world of peptides. I'm sure you guys will have a bunch of questions after this as well. And Krista, you, you obviously do this in your clinic with your patients, so if someone is wanting to just get a little bit more of an understanding of how this all works, like.
Definitely reach out to Krista. We'll pop a link below if you wanna book an initial consult. And just, you know, peptides can be life changing. We've heard firsthand, especially if you're listening to part one, how much this can reduce some of those massive markers of metabolic dysfunction or disease in the body.
And so it's not just this beautiful skin glow though, though, that might be why I start taking mim. Also really preventative or even reversible, like reversing some of [00:18:00] those really high markers in the body that aren't serving us. So. Is there anything else you wanted to add to, to the little peptide chat that we've had?
Krista?
CHRISTA ELZA: No, I think hopefully this conversation has opened your eyes to some, like how a few of these work. I know we talked a little bit more about how GLP ones work in the previous episodes, so go back and listen to that one. One just key thing about peptides is there's so much noise, there's so much online about this.
I think it's important to work with a provider who understands peptides, who understands them for you. Also is getting 'em from sources that are trusted because sometimes they're not. Either they're not potent enough or they contain heavy metals. You just don't know where these are coming from. So you just wanna be sure that you're working with a provider and a pharmacy that's trusted to get some of these.
And also with a provider to that understands like the. How to push these and pull them back and how to rotate them, right? Some of these aren't meant to be taken all the time. Some of these are meant to be pulsed for a while and then stopped to protect the receptors in your body. Sometimes [00:19:00] we need to monitor lab work while you're on these to ensure safety.
So that would just kind of be my final say here. Just make sure that you're doing these safely and from a provider that understands them.
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